"This book strengthens the scientific knowledge base and promotes rational thinking among students. Highlights of the 27th Edition What's New ?Multi-coloured Revised Edition as per CBME Curriculum and Readers'Feedback ?Pharmacology Simplified with Explanations to Promote Understanding ? Supported by Tables and Boxes, Coloured Figures and Video Links ?Therapeutics as per National Guidelines with Relevant Global Trends ? List of Learning Objectives and Key Terms ? Drug Classification in the form of Flow Charts ?Core Points and Therapeutics Highlighted ? Knowledge-related Competencies Labelled ? Section-wise Case-based MCQs Important Additions/Updations ? General Pharmacology Revised ? Updates on Pharmacotherapy of Migraine ? Mechanism of Action of Antidepressants Simplified ? Updated Treatment Guidelines for Anaphylaxis ? Guidelines for Use of PPI with NSAIDs: At a Glance ? Rational Use of Antimicrobials for Common Infections ? Syndromic Management of STIs plus Detalled Pharmacotherapy of Individual Diseases ? Abnormal Uterine Bleeding Management ? Guidance on Selecting a Contraceptive Method ? Pathogenesis and Pharmacotherapy of Osteoporosis ?Drug Selection based on Symptom Profiling for Heart Failure, Hypertension, Diabetes Mellitus, Asthma, etc. ? Updates on Newer Vaccines, including Corona Vaccines ELSEVIER elsevier.com The 27th edition of Pharmacology and Pharmacother- apeutics, mainly for the undergraduate medical stu- dents of 2nd and 3rd phase, is an Integrated approach to present an updated knowledge of the pathophysiology of the diseases, pharmacology of available drugs and strategies for disease management. This will help in developing a strong scientific knowledge base and promoting rational thinking, both of which are required to become competent IMGs. This edition has undergone extensive revision with update on the drug Information. Care has been taken to give equalweightage to therapeutics. There are ad- ditional coloured figures, boxes and tables to engage the students with the text and facilitate easy grasping. All the positive features of earlier edition have been retained. In this edition, case-based MCQs on each sec- tion have been added to challenge the readers to think critically and self-assess their learning. Attention has been paid to keep the text simple and student friendly. Salient Features ? Structured pedagogy facilitating feature-rich presen- tation and organization of the content, which makes It more student friendly ?Richly Illustrated content supplemented with large number of tables and boxes - explaining physiology. complex concepts, relevant drug features and prin- ciples of pharmacotherapy ? Mechanisms of drug actions, explained in text and Illustratedvladlagrams as well as videos (animations) for better understanding and retention ?Key points in pharmacology and pharmacotherapy of diseases highlighted throughout the book ?Practical tips in this book serve as a reference guide in practice so that the budding doctors and practising phy- sicians can treat their patients effectively and confidently"